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Departmental Colloquium

Physics and applications of contrast-enhanced MRI - Detection and Evaluation of Tumors Labeled with iron-Oxide Nanoparticles in MRI  
Guest Speaker
Mr. Jason Langley  
Guest Affiliation
UGA, Physics and Astronomy  
Thursday, August 19, 2010 4:00 pm - 5:00 pm  
Physics 202  

Contrast agents are used in magnetic resonance imaging (MRI) to enhance contrast difference in tissues by changing relaxation rates between tissues with and without contrast agent. Contrast agents can be broken into two categories: T1–based agents and T2–based agents. T1–based contrast agents change the longitudinal relaxation time (T1) and T2–based contrast agents change the transverse relaxation time (T2). In this talk, we will focus on contrast agents based on super paramagnetic iron oxide (SPIO) nanoparticles. SPIO nanoparticles change T2 of surrounding tissues and are used to label different types of cells. In the talk, methods for detecting labeled cells and quantifying concentrations of labeled cells will be presented.